To conduct a scoping review of the existing literature and recent developments on prostatic stents for the treatment of benign prostatic hyperplasia (BPH).
A comprehensive search was performed on Embase, MEDLINE, and Web of Science to identify English literature on prostatic stents for the treatment of BPH. Additional studies and upcoming devices were identified through grey literature search and expert consultation. Study characteristics and stent information were extracted and tabulated narratively.
Of the 1171 search results, 64 studies were included in this review. iTiND was the prostatic stent with the most long-term evidence. iTiND is a safe and effective minimally invasive treatment for BPH that preserves sexual function. Adverse events are mild and transitory. Emerging stents (e.g. Zenflow, Butterfly, Urocross, and Exime) had 7/64 eligible studies, where no studies had long-term follow-up. These newer stents show promising results for quality of life and BPH symptom management; however, long-term monitoring and head-to-head comparisons are needed.
Over the last 50 years, prostatic stents have evolved and demonstrated improved clinical efficacy. iTiND provides a safe and effective outpatient treatment of LUTS secondary to BPH preserving erectile and ejaculatory function. Emerging prostatic stents are a promising, effective, and safe intervention in well-selected patients interested in its benefits.
World journal of urology. 2023 Jul 21 [Epub ahead of print]
Anna-Lisa V Nguyen, Isha Verma, Roseanne Ferreira, David-Dan Nguyen, Kevin C Zorn, Naeem Bhojani, Lori B Lerner, Vineet Gauhar, Bilal Chughtai, Dean S Elterman
Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada., Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada., Division of Urology, Department of Surgery, University of Toronto, Toronto, ON, Canada., Division of Urology, Centre Hospitalier de l'Université de Montréal, Université de Montréal, Montreal, Canada., Department of Surgery, Veterans Affairs Boston Healthcare System, Boston, MA, USA., Division of Urology, Ng Teng Fong General Hospital, National University Health System, Jurong East, Singapore., Department of Urology, Weill Cornell Medicine, New York City, NY, USA., Division of Urology, Department of Surgery, University of Toronto, Toronto, ON, Canada. .