Holmium laser enucleation of the prostate is valid and safe procedure for the treatment of benign prostatic hyperplasia. This study aimed to examine the perioperative outcomes of holmium laser enucleation of the prostate using a new laser platform, Lumenis Pulse 120H, and a previous laser platform, VersaPulse Select 80W.
A total of 612 patients who underwent holmium laser enucleation were enrolled, including 188 and 424 patients who underwent enucleation using Lumenis Pulse 120H and VersaPulse Select 80W, respectively. They were matched using propensity scores with preoperative patient characteristics, and the differences between the two groups, including operative time, enucleated specimen, transfusion rate, and complication rate, were examined.
Propensity-score-matched cohort comprised 364 patients with 182 in the Lumenis Pulse 120H group (50.0%) and 182 in the VersaPulse Select 80W group (50.0%). Operative time was significantly shorter with Lumenis Pulse 120H (55.2 ± 34.4 vs. 101.4 ± 54.3 minutes, p < 0.001). In contrast, no significant differences were seen in resected specimen weight (43.8 ± 29.8 vs. 39.6 ± 22.6 grams, p = 0.36), rate of incidental prostate cancer (7.7% vs. 10.4%, p = 0.36), transfusion rate (0.6 vs. 1.1%, p = 0.56), and perioperative complication rates, including urinary tract infection, hematuria, urinary retention and capsular perforation (5.0 vs. 5.0%, 4.4 vs. 2.7%, 0.5 vs. 4.4%, 0.5 vs. 0%, respectively, p = 0.13).
Lumenis Pulse 120H improved the operative time significantly, which is regarded as one of the disadvantages of holmium laser enucleation of the prostate.
Journal of endourology. 2023 Jul 10 [Epub ahead of print]
Taro Banno, Kazutaka Nakamura, Akihiko Ozaki, Yukiko Kouchi, Tadashi Ohira, Hiroaki Shimmura
Tokyo Women's Medical University Hospital, 36595, Urology, Kwada-cho 8-1, Shinjuku-ku, Japan, 162-8666; ., Jyoban Hospital of Tokiwa Foundation, Department of Urology, Iwaki-city, Japan; ., Jyoban Hospital of Tokiwa Foundation, Department of Breast Surgery, Jyoban-Kamiyunaga-Yamachi-Yudaido, Iwaki, Fukushima, Japan, 972-8322., Jyoban Hospital of Tokiwa Foundation, Department of Urology, Iwaki, Japan; ., Ohira Clinic, Department of Urology, Mito, Japan; ., Jyoban Hospital of Tokiwa Foundation, Department of Urology, Iwaki, Japan; .