Port-Site Metastasis Identified on Prostate-Specific Membrane Antigen-Targeted 18F-DCFPyL PET/CT After Robot-Assisted Laparoscopic Radical Prostatectomy.

Port-site metastasis is an extremely rare complication following minimally invasive oncologic surgery for prostate cancer. We present the case of a 74-year-old man who underwent robot-assisted laparoscopic radical prostatectomy followed by salvage radiotherapy. Despite treatment, he developed biochemical recurrence. However, there was no evidence of disease on CT and bone scan at a prostate-specific antigen of 4.6 ng/mL. Subsequently, 18F-DCFPyL PET/CT revealed a solitary focus of intense uptake in the right rectus abdominis muscle that was felt to represent a port-site metastasis. Histopathologic evaluation with immunostaining following ultrasound-guided needle biopsy confirmed the presence of metastatic adenocarcinoma of the prostate.

Clinical nuclear medicine. 2023 Jan 12 [Epub ahead of print]

Hanan Zahed, Jerome Laufer, Martin LeBlanc, Steven Tisseverasinghe, Tamim Niazi, Stephan Probst

From the Departments of Nuclear Medicine., Radiation Oncology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.