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EAU 2018: Relationship of Endoscopic Lesions of The Renal Papilla With Type Of Renal Stone and 24h Urine Chemistry

Copenhagen, Denmark (UroToday.com) Dr. Sabaté Arroyo, clinical urologist from the Hospital Universitari Son Espases in Palma de Mallorca, Spain, depicted a study conducted at his center regarding the relationship of the different types of endoscopic calcification in the renal papilla. The types of calcifications explored were Randall’s plaque, tubular calcification, or papillary crater. To determine these relationships, the stone chemistry was determined (calcium oxalate monohydrate, calcium oxalate dehydrate, uric acid, and calcium phosphate) and the patient was subjected to a 24-hour urine analysis of calcium, oxalate, citrate, and pH.

By the time of completion of this prospective study, 41 patients were recruited who all were undergoing retrograde intrarenal surgery for renal lithiasis. Each papillary injury that was discovered via endoscopy was analyzed and grouped into one of the three types of papilla injury locations. Of the collected data, significance was found between tubular calcification patients and a prevalence of calcium oxalate dehydrate stones. Additionally, papillary crater injuries were most often due to calcium oxalate dehydrate stones as well. Tubular calcification was the most prevalent injury recorded from the patient set. In regard to patient 24-hour urine results, it was shown that tubular calcification is positively associated with hypercalciuria, Randall’s plaque is positively associated with hypocitraturia, and papillary crater is positively associated with hypoxaluria.

Speaker: X.A. Sabaté Arroyo

Authors: Sabaté Arroyo X.A., Pieras Ayala E.C., Grases Freixedas F., Tubau Vidaña V., Bauza Quetglas J.L., Guimerá García J., Pizá Reus P.

Written by: Zachary Valley, Department of Urology, University of California-Irvine, at the 2018 European Association of Urology Meeting EAU18, 16-20 March, 2018 Copenhagen, Denmark