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- (Length of Discussion: 10 min) David Penson and Alicia Morgans share views on the evolution of the United States Preventive Services Task Force, USPSTF's recommendations for PSA screening. What do the recent changes mean to the clinician and the patient when making individual decisions regarding screening. Biographies: David F. Penson, MD, MPH, is the Paul V. Hamilton, M.D. and Virginia E. Howd Ch...
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- (Length of Discussion: 12 min) Susan Halabi, the first biostatistician to become a fellow of ASCO, discusses recent data on overall survival in prostate cancer for black versus white men with Alicia Morgans and Charles Ryan. Susan discusses an analysis that showed an increase in overall survival in African American men vs Caucasian men, all of whom had metastatic castration-resistant prostate canc...
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- Cora Sternberg highlights from a number of key treatments in GU Oncology in a discussion with Alicia Morgans. Results from the only Phase 3 health-related quality-of-life (HRQoL) analyses in urothelial carcinoma from the KEYNOTE-045 study delivers results for patients who received 2 nd line therapy. A relevant discussion follows on a Phase 2 trial investigating 3 different dosing regimens of radiu...
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- (Length of Discussion: 3 min) Diane Newman and Eric Rovner discuss a newly published book on urologic devices and catheters. This book is written for the urology and gynecology community and mindfully designed to be a great resource for patients as well. The book houses a breadth of topics from urologic devices, skin care, catheter options, and procedures. Biographies: Diane K. Newman, DNP Eric S....
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- Diane Newman talks with Susann Varano about the serious problem that many geriatric patients suffer from, nocturia and other symptoms of lower urinary tract conditions. They discuss the most effective way to assess the patient in hopes to find the right treatment solution. Dr. Varano provides her clinical opinion on a new agent available on the market and her experience both from a research perspe...
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- (Length of Discussion: 15 min) Tom Keane and See-Tong Pang discuss the results of a prospective clinical study utilizing a novel circulating tumor cells (CTC) blood assay to clarify PSA results in 200 men who present with a PSA of 4ng/ml-10ng/ml. The CellMax CTC Platform is used to isolate CTCs to assess NPV and PPV for Gray Zone patients. Isolated CTCs may also be analyzed for the presence of pro...
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- (Length of Discussion: 16 min) An emerging expert in the field of genetics and prostate cancer, Heather Cheng speaks with Charles Ryan in a thought-provoking dialogue of genetic evaluation and counseling for patients with prostate cancer. They review a variety of the genes that are involved in both DNA repair as well as the Lynch Syndrome, wrapping up with a discussion about PARP Inhibitors. Biogr...
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- Charles Ryan, MD, and Oliver Sartor, MD discuss bone health in the treatment of prostate cancer and then transition to discuss the novel theranostic opportunities that are in development for the treatment of prostate cancer including Lutetium-177 PSMA and Actinium PSMA-225. Lastly, they have a concise conversation about DNA mutations in prostate cancer and the implications of germ-line and somatic...
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- (Length of Presentation: 10 min) Alicia Morgans, MD and Bishoy Faltas, MD have an energetic conversation about the tremendous progress they have seen in the recent years in bladder cancer. Dr. Faltas takes us through some of the current research with IO therapy, specifically checkpoint inhibition; where they are currently used and where the clinical data may expand the use of these agents. He revi...
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- (Length of Discussion: 30 min) Tom Keane, MBBCh, FRCSI, FACS provides a detailed overview of the CARMENA study, presented by Arnaud Mejean MD, Ph.D. at ASCO 2018. This Phase III randomized trial assessed the utility and timing of CNx in the treatment paradigm of mRCC comparing patients who were randomized to either CNx and sunitinib vs sunitinib alone without CNx. He discusses the clinical applica...
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