- Details
- Andrea Necchi and Alicia Morgans discuss the evolution of neoadjuvant treatment for muscle-invasive bladder cancer (MIBC) including the role of immunotherapy and chemotherapy prior to radical surgery. They discuss the PURE-01study which included all-comers regardless of cisplatin eligibility. The early data from PURE-01 with neoadjuvant pembrolizumab demonstrated a 42% pathological complete respon...
|
- Details
- Arnulf Stenzl is the co-facilitator of the case-based specialty session. Here he discusses improving outcomes in non-muscle invasive bladder cancer with the en bloc resection for cancers that are smaller than one centimeter which is consistent with the EAU guidelines. Dr. Stenzl has been performing en bloc resections for tumors up to 3 centimeters which provides more information on staging. He als...
|
- Details
- Matthew Cooperberg discusses active surveillance as the standard of care for men with low-risk prostate cancer as well as data from multiple registries including CaPSURE, MUSIC, AQUA, and SEER, which report increasing rates of active surveillance in men with low-risk disease. He further discusses the factors that may be driving lower uptake of active surveillance in some practices. Biographies: Ma...
|
- Details
- Jeannette Potts discusses her work within the field of pelvic pain and specifically men suffering from urological chronic pelvic pain syndromes (UCPPS) and how it is commonly misdiagnosed. Jeannette stresses the need to think beyond the prostatitis classification system and instead consider pelvic pain symptoms and its multiple causes and contributors. In addition, she reviews the categorization o...
|
- Details
- Scott MacDiarmid and Diane Newman discuss the urologist's role in the management of nighttime frequency or nocturia. Dr. MacDiarmid discusses the need for urologists to start thinking differently when it comes to the management of nocturia. He calls for the urologists to recognize that they are the experts in this area, identify the patients, and be proactive in treatment. He discusses both isolat...
|
- Details
- Alicia Morgans and Sam Chang discuss the diagnostic and therapeutic challenges of upper tract urothelial carcinoma (UTUC). UTUC is relatively uncommon compared to urothelial carcinoma, accounting for 5-7% of all cases. The disease can be quite insidious and present a challenge to diagnose. Dr. Chang discusses the use of CT urograms in the diagnosis and how size, grade, and stage of the tumor is us...
|
- Details
- Alicia Morgans presents a lecture on the contemporary management strategies for hormone sensitive prostate cancer with a focus on systemic therapy including chemohormonal approaches and the use of abiraterone for metastatic hormone sensitive disease. In the discussion, Alicia compares and contrasts both the CHAARTED and STAMPEDE data and provides an update on treatment today, including evidence ba...
|
- Details
- Ananias Diokno shares his journey into and through urology with Diane Newman in this interview. His leadership and contributions in urology are inspirational to all of us working to impact improved patient outcomes. Dr. Diokno shares his recent work in to our understanding incontinence and treatments. The GLADIOLUS study shows that a novel one-time, group-administered behavioral treatment (GBT) pr...
|
- Details
- The UROFLOW STOP TEST (UST) aims to highlight the patient's ability to completely hold back the urine, thus giving us an idea of his continence capacity. This concerns the pelvic floor muscles, as well as primarily the sphincter function. This test is performed during a normal Uroflowmetry (UF) test, by merely asking the patient to retain urine after an acoustic signal and then be asked to maintai...
|
- Details
- Brant Inman discusses the role of the surgeon in the management of metastatic bladder cancer. Oftentimes surgical management is overlooked in favor of systemic therapies, including chemotherapy and immunotherapy. However, in certain cases, a surgical approach may provide a higher cure rate. Dr. Inman and Dr. Kamat discuss appropriate patient selection and scenarios for surgery and the role of neoa...
|