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- Michael Morris joins Alicia Morgans to discuss advanced molecular imaging, and how we can take the data we have and integrate it into our clinical practices. They discuss recent results of the Prostate Cancer Working Group as well as the patient where advanced molecular imaging is most useful. Finally, Dr. Morris provides his recommendation to clinicians gaining access to these scans and how to us...
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- Fernando Maluf joins Charles Ryan to discuss the data from the first Prostate Cancer Global Consensus Conference for Developing Countries. This was a tremendous achievement in which more than a hundred physicians from all over the world, particularly from developing countries in Latin America, Africa, and the Middle East participated. Physicians that participated included several specialties: urol...
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- In the era that genomics and genetics are really making an impact to clinical practice and with the recent positive results of the PROfound study, Alicia Morgans and Colin Pritchard have a discussion thinking about this data, how do we implement it, and how do we work with our pathologists to make things happen? Colin highlights this game-changing genomic markers data, particularly for homologous...
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- Alicia Morgans and Brad McGregor discuss rare genitourinary histologies and the efforts to find treatment options for populations not always included in clinical trials. Most clinical trials are developed and designed for the most common subtypes, not including atypical variant histologies often found in bladder and prostate cancers. Given the tumor agnostic approach of immunotherapy, Brad and his...
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- Ashish Kamat invites Stephen Williams to present on costs and survival analysis between radical cystectomy and trimodal therapy. He shares results of two studies which patients from 2002-2011 were looked at in both studies focusing on methodology/statistical analyses and the outline of outcomes. This work found that trimodal therapy had significantly worse survival, these findings persisted across...
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- During the Management of Metastatic Castration-sensitive/naive Prostate Cancer session at the 2019 Advanced Prostate Cancer Consensus Conference, William Oh presented the use of androgen deprivation therapy (ADT) alone vs. the use of ADT in addition to one of the available systemic therapies for metastatic prostate cancer. Biography: William K. Oh, MD, Chief Medical Officer (CMO), of the Prostate...
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- During the Management of metastatic castration-sensitive/naive prostate cancer session at the 2019 Advanced Prostate Cancer Consensus Conference (APCCC), Matthew Sydes presented a statisticians' perspective on Addition of AR pathway inhibitors vs. docetaxel. Video Length 10:53 minutes Biography: Matthew R Sydes, MSc CStat CSci, MRC Clinical Trials Unit at UCL London Related Content: Written Confer...
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- William Oh highlights the first study of people who were exposed to the World Trade Center dust and who subsequently developed prostate cancer. World Trade Center responders with prostate cancer showed signs that inflammation was activated in the prostate after exposure to dust from the World Trade Center site, possibly causing chronic inflammation that contributed to their cancer, according to a...
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- During the 2019 Advanced Prostate Cancer Consensus Conference (APCCC) Himisha Beltran presented an overview looking into the future of oligometastatic disease, and where she predicts we will be in two years’ time. Her presentation focused on refined clinical definitions for disease stratification, nominated molecular biomarkers to capture biologic disease states and defined goals of care for impro...
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- Fred Saad presented on bone and bone metastases at the Advanced Prostate Cancer Consensus Conference (APCCC) 2019 focusing on the prevention and treatment of osteoporosis. Given the relationship between ADT and bone loss, previous studies have established that ADT leads to increased fracture rates. Along with a proposed approached for men on ADT, Dr. Saad recommends the use of Fracture Risk Assess...
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