AUA 2011 - Persistent therapeutic effect of repeated injections of onabotulinum toxin A in refractory bladder pain syndrome/interstitial cystitis - Session Highlights

WASHINGTON, DC USA (UroToday.com) - Dr. Francisco Cruz and co-workers from Porto, Portugal related further experience with intra-trigonal onabotulinum toxin A in 14 women with IC/BPS refractory to first-line treatments.

AUA 2011 - Phase III study of intermittent MAB vs. continuous MAB - Session Highlights

WASHINGTON, DC USA (UroToday.com) - Intermittent androgen ablation (IAB) not continuous therapy should be considered routine for patients with advanced prostate cancer according to this important report.

AUA 2011 - Phenotyping men with interstitial cystitis/painful bladder - Session Highlights

WASHINGTON, DC USA (UroToday.com) - Ragi Doggweiler and colleagues from Knoxville, Tennessee phenotyped 96 men with IC/BPS

AUA 2011 - Potency outcomes in patients who had multiple biopsies before radical prostatectomy for the treatment of localized prostate cancer - Session Highlights

WASHINGTON, DC USA (UroToday.com) - What is the effect of numerous prostate biopsies on eventual erectile function following radical prostatectomy this group asked?

AUA 2011 - Prostate cancer detection rates, risk factors, and distribution with transperineal mapping template prostate biopsy: initial single institution experience - Session Highlights

WASHINGTON, DC USA (UroToday.com) - Transperineal mapping template prostate biopsy (TMTPB) can detect significant prostate cancer in patients with previous negative biopsies, according to Dr. Michael Rowley from the University of Michigan.

AUA 2011 - Researchers advance treatments for incontinence due to spinal cord defects, disease and deformed bladders - Press Release

WASHINGTON, DC USA (UroToday.com) - May 16, 2011 - Employing a variety of the most sophisticated experimental techniques and procedures, researchers have advanced treatments for children in need of bladder reconstruction.

AUA 2011 - Smoking linked to biochemical recurrence of prostate cancer - Press Release

WASHINGTON, DC USA (UroToday.com) - May 16, 2011 - Men who smoke are more likely to have adverse pathology findings and a higher risk that PSA levels will elevate following radical prostatectomy for prostate cancer,

AUA 2011 - State-of-the-art-lecture: Association of metabolic syndrome, coronary artery disease and kidney stone formation - Session Highlights

WASHINGTON, DC USA (UroToday.com) - Dr. Dean Assimos made a very good case for the relationship between metabolic syndrome, coronary artery disease and kidney stone formation.

AUA 2011 - State-of-the-art-lecture: How do I manage a failed mid-urethral sling? - Session Highlights

WASHINGTON, DC USA (UroToday.com) - Dr. Eric Rovner began his lecture by asking how the urologist measurse or assesses the imperfect result of mid-urethral slings (MUS) and who should do it: the patient or the doctor?

AUA 2011 - Target specific and dye encapsulated micelle probes for the detection of extra-prostate cancer during robotic-assisted laparoscopic prostatectomy (RALP) - Session Highlights

WASHINGTON, DC USA (UroToday.com) - Dr. William Johnston reported a new fluorescence probe locked within a micelle to improve fluorescent intensity of prostate tissue.

AUA 2011 - The effects of caffeine on the symptoms of interstitial cystitis/painful bladder syndrome: a randomized, placebo-controlled double blind study - Session Highlights

WASHINGTON, DC USA (UroToday.com) - Amin Herati and co-investigators from New York reported on a randomized, placebo-controlled, double blind study assessing the effects of caffeine (100mg or about the equivalent of a cup of coffee) on irritative voiding symptoms and pelvic pain.

AUA 2011 - The value of computed tomography in detecting prostate cancer lymph node metastasis is limited even in contemporary patients with very high risk of nodal involvement - Session Highlights

WASHINGTON, DC USA (UroToday.com) - Dr. Alberto Briganti told the audience that the sensitivity and accuracy of CT scans in predicting positive lymph nodes at surgery is low even in contemporary patients with a very high risk of nodal involvement.

AUA 2011 - Utilizing metformin to enhance the efficacy of androgen deprivation therapy in the treatment of prostate cancer - Session Highlights

WASHINGTON, DC USA (UroToday.com) - Cancer cells under stress utilize autophagy, a mechanism to degrade intracellular proteins to generate energy to survive.

AUA 2011 - Extended sampling biopsies, MRI show promise in managing low-risk prostate cancer - Press Release

WASHINGTON, DC USA (UroToday.com) - May 16, 2011

Methods May Alleviate Uncertainties in Cases of Active Surveillance, “Watchful Waiting”

AUA 2011 - Abiraterone demonstrates effective results with favorable safety profile in men with castration-resistant advanced prostate cancer - Press Release

WASHINGTON, DC USA (UroToday.com) - May 16, 2011 - Abiraterone acetate (AA) with low-dose prednisone (P) extended overall survival with favorable PSA and radiographic responses in patients with castration-resistant prostate cancer progressing after docetaxel-based chemotherapy, according to updated data from COU-AA-301, a multi-institutional, randomized, double-blind, placebo-controlled, phase III study from researchers at 147 institutions across 13 countries.

AUA 2011 - Prostate cancer: To treat, not to treat and when to treat? - Press Release

WASHINGTON, DC USA (UroToday.com) - May 16, 2011

Panel to Address Key Questions about Low-Risk Prostate Tumor Management

AUA 2011 - Androgen independent, tumor-reinitiating cells are selected by androgen deprivation in models of androgen dependent prostate cancer - Session Highlights

WASHINGTON, DC USA (UroToday.com) - This research importantly shows that androgen deprivation therapy (ADT) selects for stem/progenitor (S/P) and neuroendocrine (NE) cells that can reinitiate tumor growth in an androgen-independent fashion.

AUA 2011 - Andrographolide targets AR pathway in castration-resistant prostate cancer - Session Highlights

WASHINGTON, DC USA (UroToday.com) - These researchers showed the effect of a phytotherapy on castration-resistant prostate cancer (CRPC).

AUA 2011 - Association of the number of lymph nodes (LN) removed at radical prostatectomy with all-cause (ACM) and prostate cancer-specific mortality (PCSM) - Session Highlights

WASHINGTON, DC USA (UroToday.com) - This multicenter group of investigators presented data that the extent of pelvic lymph node dissection (PLND) in men undergoing radical prostatectomy was not associated with ACM or PCSM.

AUA 2011 - Benefit of denosumab therapy in patients with bone metastases from castrate resistant prostate cancer: A number-needed-to-treat (NNT) analysis - Session Highlights

WASHINGTON, DC USA (UroToday.com) - This report by Dr. Kurt Miller and colleagues suggests that the number needed to treat (NNT) with denosumab to prevent one skeletal-related event is five.