Munich, Germany (UroToday.com) Dr. Kyriazis and associates presented their work on improving the detection of pelvic lymph node invasion in radical prostatectomy during this poster session of the 2016 EAU annual meeting.
This was a retrospective study of 2160 robotic or laparoscopic PLNDs performed over an 11-year period. The investigators compared nodal count by approach on a univariate basis, and then used regression analysis to identify predictors of nodal invasion. Covariates of interest included risk group, T stage, approach, use of robotic assistance, history of inguinal mesh, surgeon, and node count.
The study investigators found that detection rate and proportion of LNDs with positive nodes increased over the study period. Interestingly, rates of pT3 disease shared a similar trend to rates of pN1. Transperitoneal approach had better LN yield than extraperitoneal (including when stratified by risk group), while laparoscopic and robotic had similar yield. Other factors examined did not impact the detection of lymph node invasion.
The authors concluded that surgical approach and the ability to identify high-risk patients is integral to the improvement in detection of pelvic lymph node invasion among men undergoing radical prostatectomy.
Presented By:
Stolzenburg J.U., Kyriazis I., Gilfrich C., Popken G., Weißbach L., Von Zastrow C., Fahlenbrach C., Günster C., Jeschke E., Leicht H.
Reported By:
Nikhil Waingankar, MD, at the 31st Annual EAU Congress - March 12 - 15, 2016 – Munich, Germany
Fox Chase Cancer Center